Received: 10-06-2020 / Accepted: 19-08-2020
Lien Minh chicken is an indigenous breed with several favorable propertiesand associated with the economic development of the people in the Lien Minh village, Cat HaiDistrict, Hai PhongCity. Chicken Insulin (INS) and Insulin-like growth factor binding protein 2 (IGFBP2) are physiological candidate genes involved in the growth traits. This study aimed to investigate the association of single nucleotide polymorphism (SNP) of INS and IGFBP2genes concerned with bodyweight inLien Minhchicken.The indexes for 100 Lien Minh chickens were observed individually about their body weights from 01 day to 20 weeks age.Blood samples were used for DNA extraction and then genotyping by PCR-RFLP method. Two SNPs of INSandIGFBP2genes were analyzed. Allele frequencies ofINSand IGFBP2were: A (0.65), G (0.35) and A (0.46), T (0.54), respectively. Genotype GG INSshowed the highest values of mean body weight at 14, 16weeks of age for hen, 18 weeks of age for cock (P <0.05), and genotype AAof IGFBP2 (IGFBP2)wasalsoshown thehighest values of mean body weight at 20 weeks of age. These results suggested that the beneficial alleles/genotypes could be used to support the improvement of the egg production capacity in the breeding of Lien Minh chicken.