Molecular Characterizations of Porcine Epidemic Diarrhea Virus (PEDV) Isolated in Hung Yen Province

Received: 19-05-2020

Accepted: 02-06-2020

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Issue: Vol. 18 No. 7 (2020)

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CHĂN NUÔI – THÚ Y – THỦY SẢN

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Giap, N., Anh, D., Thai, T., & Le, H. (2024). Molecular Characterizations of Porcine Epidemic Diarrhea Virus (PEDV) Isolated in Hung Yen Province. Vietnam Journal of Agricultural Sciences, 18(7), 463–474. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/682

Molecular Characterizations of Porcine Epidemic Diarrhea Virus (PEDV) Isolated in Hung Yen Province

Nguyen Van Giap (*) 1 , Dang Huu Anh 1 , Truong Ha Thai 1 , Huynh Thi My Le 1

  • 1 Khoa Thú y, Học viện Nông nghiệp Việt Nam

    • Keywords

    Porcine Epidemic Diarrhea Virus, molecular characterizations, Vietnam

    Abstract


    Since the first detection in 2009, PEDV has been circulating in the North, Centre and the South of Vietnam. The disease has caused significant damages to the pig production sector. In order to mitigate the economic damage caused by diseases, the manufacture and use of field- matching vaccines are necessary. Aimed at providing more information on the biology of pathogenic PEDV strains in Vietnam, this study analyzed the molecular biology of the gene encoding S1 domain of one PEDV isolate detected in Hung Yen in 2017. The results showed that the field isolate, PEDV_HY2017, is genogroup G2 PEDV. The virus shared nucleotide similarity with PEDV strains of Vietnam in the ranges of 90-91% and 95.7-98.2% in compared to genogroup G1 and genogroup G2, respectively. The PEDV_HY2017 strain carries two regions of insertion-deletion mutations in the gene segment encoding the S1 domain of the Spike protein. This characteristic was similar to the other Vietnamese PEDV genogroup G2 viruses.

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