Received: 31-07-2019 / Accepted: 20-09-2019
This study was conducted to reveal the clinical and non-clinical characteristics as well as gross lesions of chickens infected by chicken infectiousaAnemia virus (CIAV) under an experimental condition. Via intra-abdominal inoculation of the virus at a dose of 104TCID50/mL, one-week oldchickens were sucessfully infected by the field strain of CIAV with the viremia appeared at 3 weeks postinfection (20.0%) and reached 100% at the sixth week postinfection. Under the current condition, viremic CIAV chickens exhibited minimum clinical signs. From the fifth week after infection, CIAV infected group exhibited a reduction inthe growth rate and had significantly lower body weight than that of the control group. Additionally, at eighth week postinfection, the packed cell volume of CIAV positive group was less than 27% and was significantly lower than the control group. The chickens of the experimental group had compatible gross lesions of anemia, such as pale of bone marrow (77.8%) and atrophy of primary lymphoid organs (bursa of Fabricius and thymus, 33.3% and 55.6%, respectively). The results of this study appeared helpful for differential diagnosis of chicken infectious anemia in the field.
