Pathological Features and Biological Characteristics of Feline Panleukopenia VirusIsolate from Cat in Hanoi

Received: 20-10-2020

Accepted: 03-06-2021

DOI:

Views

0

Downloads

0

Issue: Vol. 19 No. 8 (2021)

Section:

CHĂN NUÔI – THÚ Y – THỦY SẢN

How to Cite:

Yen, N., Son, N., Ngoc, N., Hung, L., Giang, N., & Hung, P. (2024). Pathological Features and Biological Characteristics of Feline Panleukopenia VirusIsolate from Cat in Hanoi. Vietnam Journal of Agricultural Sciences, 19(8), 1006–1015. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/861

Pathological Features and Biological Characteristics of Feline Panleukopenia VirusIsolate from Cat in Hanoi

Nguyen Thi Yen (*) 1 , Nguyen Vu Son 1 , Nguyen Thi Ngoc 1 , Le Van Hung 1 , Nguyen Thi Giang 1 , Pham Quang Hung 1

  • 1 Khoa Thú y, Học viện Nông nghiệp Việt Nam

    • Keywords

    Feline panleukopenia, pathology, FPV, parvovirus, virus isolation

    Abstract


    The study was conducted in order to determine the pathological and biological features of the feline panleukopenia virus causing disease in domestic cats in Hanoi. In the present study,eight cats from 2 months to 1 year-old-age were observed for clinical symptoms, and collected samples were collected for a histopathology examination. The results showed that feline leukopenia caused by FPV hadsymptoms of vomiting, dehydration, and diarrhea, etc. Gastrointestinal lesions included congestion, mucosal hemorrhage, bloody substance contents. The major microscopic lesions were proliferation of the intestinal lymphatic nodules, with epithelial cell degeneration, collapsed villiofthe intestine. The number of lymphocytes decreased sharply in the mesenteric lymph nodes, whereas monocytes and macrophages increased. The virus isolationresults on CRFK cells have obtained 5 different virus strains with titers ranging from 1.77 108to 1.77 109TCID50/ml. The present findings on the growth curve of the virus showed that with the multiplicity of infectious dose MOI = 0.001, the highest viral titration was 1010,5TCID50/ml after 36 hours post-infection.

    References

    Barrs V.R. (2019). Feline Panleukopenia: A Re-emergent Disease. The Veterinary clinics of North America. Small animal practice. 49(4): 651-670.

    Bennet M.& Gaskell R. (1996). Feline and Canine Infectious Diseases. In: Berlin, Germany: Blackwell Wissenschafts-verlag.

    Bentinck-Smith J. (1949). Feline panleukopenia (feline infectious enteritis) - a review of 574 cases. North Am Vet. 30: 379-384.

    Cave T., Thompson H., ReidS., Hodgson D.& Addie D. (2002). Kitten mortality in the United Kingdom: a retrospective analysis of 274 histopathological examinations (1986 to 2000). Veterinary Record. 151(17): 497-501.

    Csiza C.K., De Lahunta A., Scott F.W. & Gillespie J.H. (1971). Pathogenesis of Feline Panleukopenia Virus in Susceptible Newborn Kittens II. Pathology and Immunofluorescence. Infection and immunity. 3(6): 838-846.

    Fei-Fei D., Yong-Feng Z., Jian-Li W., Xue-Hua W., Kai C., Chuan-YiL., Shou-YuG., Jiang S. &Zhi-JingX.(2017). Molecular characterization of feline panleukopenia virus isolated from mink and its pathogenesis in mink. Veterinary Microbiology. 205: 92-98.

    Goto H. (1974). Feline panleukopenia in Japan. I. Isolation and characterization of the virus.

    Greene C. (2006). Canine brucellosis. Infectious diseases of the dog and cat. pp. 369-381.

    Greene C. & Addie D. (1998). Feline panleukopenia. Infectious diseases of the dog and cat. pp. 52-58.

    Ichijo S., Osame S., Konishi T. & Goto H. (1976). Clinical and hematological findings and myelograms on feline panleukopenia. The Japanese journal of veterinary science. 38(03): 197-205.

    Kärber G. (1931). Beitrag zur kollektiven Behandlung pharmakologischer Reihenversuche. Archiv f experiment Pathol u Pharmakol. 162: 480-483.

    KonishiS. (1975). Studies on feline panleukopenia. I. Isolation and properties of virus strains.

    Kruse B.D., Unterer S., Horlacher K., Sauter-Louis C. & Hartmann K. (2010). Prognostic factors in cats with feline panleukopenia. Journal of veterinary internal medicine. 24(6): 1271-1276.

    Leal É., Liang R., Liu Q., VillanovaF., Shi L., Liang L., Li J., Witkin S. S. & Cui S. (2020). Regional adaptations and parallel mutations in Feline panleukopenia virus strains from China revealed by nearly-full length genome analysis. PloS one. 15(1): e0227705.

    Meurs K.M., Fox P.R., Magnon A.L., Liu S. & Towbin J.A. (2000). Molecular screening by polymerase chain reaction detects panleukopenia virus DNA in formalin-fixed hearts from cats with idiopathic cardiomyopathy and myocarditis. Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology. 9(2): 119-126.

    Mochizuki M., Horiuchi M., Hiragi H., San Gabriel M. C., Yasuda N. & Uno T. (1996). Isolation of canine parvovirus from a cat manifesting clinical signs of feline panleukopenia. Journal of Clinical Microbiology.34(9): 2101-2105.

    Parrish C.R. (1995). 3 Pathogenesis of feline panleukopenia virus and canine parvovirus. Bailliere's clinical haematology. 8(1): 57-71.

    Pedersen N.C. (2009). A review of feline infectious peritonitis virus infection: 1963-2008. Journal of feline medicine and surgery. 11(4): 225-258.

    Porporato F., Horzinek M.C., Hofmann-Lehmann R., Ferri F., Gerardi G., Contiero B., Vezzosi T., Rocchi P., Auriemma E., Lutz H. & Zini E. (2018). Survival estimates and outcome predictors for shelter cats with feline panleukopenia virus infection. Journal of the American Veterinary Medical Association. 253(2): 188-195.

    Sharp N.J., Davis B.J., Guy J.S., Cullen J.M., Steingold S.F. & Kornegay J.N. (1999). Hydranencephaly and cerebellar hypoplasia in two kittens attributed to intrauterine parvovirus infection. Journal of comparative pathology. 121(1): 39-53.

    Sykes J.E. (2014). Feline Panleukopenia Virus Infection and Other Viral Enteritides. Canine and Feline Infectious Diseases. pp. 187-194.

    Spearman C. (1908). The Method of “Right and Wrong Cases” (Constant Stimuli) without Gauss’s Formula. Br J Psychol. 2: 227-242.

    Truyen U., Addie D., Belák S., Boucraut-Baralon C., Egberink H., Frymus T.& Lloret A. (2009). Feline panleukopenia. ABCD guidelines on prevention and management. Journal of Feline Medicine & Surgery. 11(7): 538-546.

    Url A., Truyen U., Rebel-Bauder B., Weissenböck H., & Schmidt P. (2003). Evidence of parvovirus replication in cerebral neurons of cats. Journal of clinical microbiology.41(8) : 3801-3805.

    Verge J. & Christoforoni N. (1928). La gastroenterite infectieuse des chats; est-elle due à un virus filtrable. CR Seances Soc Biol Fil. 99: 312.

    Yang S., Wang S., Feng H., Zeng L., Xia Z., Zhang R.&Xia X. (2010). Isolation and characterization of feline panleukopenia virus from a diarrheic monkey. Veterinary microbiology. 143(2-4): 155-159.