Genetic Structures of Estrogen Receptor (ESR) and Prolactin Receptor (PRLR) Genes in Landrace and Yorkshire Populations at DABACO Nucleus Pig Breeding Company

Received: 02-05-2019

Accepted: 30-09-2019

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Issue: Vol. 17 No. 5 (2019)

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CHĂN NUÔI – THÚ Y – THỦY SẢN

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Thanh, N., Manh, T., Hung, N., Trang, L., Hao, P., & Ton, V. (2024). Genetic Structures of Estrogen Receptor (ESR) and Prolactin Receptor (PRLR) Genes in Landrace and Yorkshire Populations at DABACO Nucleus Pig Breeding Company. Vietnam Journal of Agricultural Sciences, 17(5), 379–385. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/561

Genetic Structures of Estrogen Receptor (ESR) and Prolactin Receptor (PRLR) Genes in Landrace and Yorkshire Populations at DABACO Nucleus Pig Breeding Company

Nguyen Chi Thanh (*) 1 , Tran Xuan Manh 2 , Nguyen Van Hung 2 , Luu Thi Trang 2 , Phan Xuan Hao 1 , Vu Dinh Ton 1

  • 1 Khoa Chăn nuôi, Học viện Nông nghiệp Việt Nam
  • 2 Công ty TNHHLợn giống hạt nhân DABACO

    • Keywords

    Estrogen receptor gene, prolactin receptor gene, Landrace, Yorkshire

    Abstract


    Litter size of pigs is an important economic trait, but its heritability is relatively low,at approximately 0.1. In addition, litter size trait can only be measured on female pigs at mature age. Therefore, genetic improvement by phenotypic selection is less effective, and at slow rate. In previous literature, it is found that ESR and PRLR genes are two QTLswith large effects on litter size in pigs. Of the two alleles A and B at ESR locus, allele B shows a positive effect on the litter size trait,while of the two alleles A and B at PRLR locus, allele A is benefical to the trait. Landrace and Yorkshire, which are imported, are two major breeds in Vietnam. The current study aimed to evaluate genetic structures of ESR and PRLR genes in two pig populations of Landrace and Yorkshire reared at the Dabaco nuclear breeding pig company, and thus examine the effects of ESR and PRLR genes on reproduction traits of the two pig populations. It was found that all three genotypes,AA, AB and BB at ESR and PRLR loci,were present in both the populations of Landrace and Yorkshire pigs. At ESR locus, allele frequency of B in the Landrace population (0.184) was lower than in the Yorkshire population (0.413). The frequency of homozygous genotype BB was 0.041 for the Landrace population and 0.655 for the Yorkshire population. At PRLR locus, allele frequencies of A and B were quite similar for the two populations. Allele frequency of A was 0.483 for Landrance and 0.516 for Yorkshire. Allele frequency of B was 0.517 for Landrance and 0.484 for Yorkshire.

    References

    BalatskyV.N, Saenko A.M. &GrishinaL.P.(2012) Polymorphism of the estrogen receptor 1 locus in populations of pigs of different genotypes and its association with reproductive traits of large white sows. Cytology and Genetics.46(4):233-237.

    Birgitte T.T.M van Rens&Tettevan der Lende(2001) Litter size and piglet traits of gilts with different prolactin receptor genotypes. Theriogenology. 57:883-893.

    Drogemuller C., Hamann H. &Distl O.(2001) Candidate gene markers for litter size in different German pig lines. Journal of Animal Science.79:2565-2570.

    Hau N.V. (2008). Onfarm performance of Vietnamese pig breeds and its relation to candidate genes. PhD Thesis, Institute of Animal Production in the Tropics and Subtropics, University of Hohenheim, Stuttgart, Germany. Cuvillier Verlag, Göttingen, Germany.

    Heley et C.S., Avalos E. &Smith C. (1988). Selection for litter size in the Pig. Animal Breeding Abstracts.56: 317-332.

    Hunyadi-Bagi Ágnes, Balogh P., Nagy K., Kusza S. (2016) Association and polymorphism study of seven candidate genes with reproductive traits in three pig breeds in Hungary.Acta Biochim Pol. 63(2):359-64. doi: 10.18388/abp.2015_1188. Epub 2016 Apr 26.

    KmiécM., Dvorak J.&Vrtková I. (2002) Study on a relation between estrogen receptor (ESR) gene polymorphism and some pig reproduction performance characters in Polish Landrace breed. Czech J. Anim. Sci.47(5): 189-193.

    Lemus-Flores C.,Mejia-MartinezK.,Rodriguez-CarpenaJ.G.,Barreras-Serrano A., Herrera-Haro J.G.& Alonso-Morales R. (2009).Genetic Diversity and Variation of ESR, RBP4 and FUT1 Genes in Mexican Creole and Yorkshire Pig Populations. Journal of Biological Sciences. 9(8):878-883.

    MazuroskiArtur, Milczewska Agata, Mroczkowski Sławomir (2013). Influence of the prolactin gene polymorphism on selected reproduction traits in sows of Polish Large white breed. Journal of Central European Agriculture.14(2):1-10.

    Mencik Sven, Vukovic Vlado, Modric Mario, Špehar Marija, Ostovic Mario, Susic Velimir, Štokovic Igor, Samardžija,Marko, Ekert Kabalin Anamaria. (2015). PRLR-AluI gene polymorphism and litter size traits in highly prolific line of topigs 20sows. Acta Veterinaria-Beograd.65(4): 463-476.

    Renato S.A. Vega, Ronne Matthews C. Castillo, Nyka Noelle B. Barrientos, Mariedel M. Llanes-Autriz, Byung-Wook Cho, Celia B. de la Viña &Neilyn O. Villa (2018). Leptin (T3469C) and Estrogen Receptor (T1665G) Gene Polymorphisms and Their Associations to Backfat Thickness and Reproductive Traits of Large White Pigs (Sus scrofaL.). Philippine Journal of Science. 147(2): 293-300.

    Rothschild M.F., Larson R.G., Jacobson C. &Pearson P.(1991). Pvu II polymorphisms at the porcine oestrogen receptor locus (ESR). Animal genetics.22: 448.

    Rothschild M.F., Jacobson C., Vaske D.A., Tuggle C.K., Short T.H., Sasaki S., Eckardt G.R. & McLaren D.G. (1994). A major gene for litter size in pigs. Proc. 5th World Congr. Genet. Appl. Livest. Prod. 21:225 - 228.

    ShortT.H., EckardtG.R., Sasaki S., Rose M., Vincent A., McLaren D.G., MilehamA.&PlastowG.S. (1995). Marker as- sisted selection for litter size in pigs. J. Anim. Sci. 73(Suppl. 1):109 (Abstr.).

    Short T.H., Southwood O.I., McLarenD.G., DeVries A., Van der Steen H., Evans G.J., MilehamA.J. & PlastowG. S.. (1997a). Evidence of a new genetic marker for litter size in pigs.J. Anim. Sci. 75(Suppl. 1):29 (Abstr.).

    Short T.H., Rothschild Max F., Southwood O.I, McLaren D.G, Vries A. de, H. van der Steen, Eckardt G.R., Christopher K. Tuggle, Helm J., Vaske D.A., Mileham A.J. & Plastow G.S. (1997b) Effect of the Estrogen Receptor Locus on Reproduction and Production Traits in Four Commercial Pig Lines1. J.Animal Sci. 75: 3138-3142

    Terman A, Polasik D., Korpal A., Wozniak . K., Prüffer K., Żak G. & Lamber B.D. (2017) Association between prolactin receptor (PRLR) gene polymorphism and reproduction performance traits of Polish swine. Can. J. Anim. Sci. 97: 169-171.

    Terman A. (2005). Effect of the polymorphism of prolactin receptor (PRLR) and leptin (LEP) genes on litter size in Polish pigs. Journal ofAnimal Breeding and Genetics. pp.400-404

    Thúy Lê Thị, Phạm Doãn Lân, Nguyễn Văn Hậu, Trần Thu Thủy, Lưu Quang Minh, Nguyễn Đăng Vang. (2002). Nghiên cứu áp dụng kỹ thuật di truyền phân tử để xác định gen liên quan đến tính trạng sinh sản của lợn nuôi tại việt nam. Tạp chí Chăn nuôi. 50(8): 7-9.

    Vincent A.L., Tuggle C.K., RothschildMax F., Evans G., Short T. H., Southwood O.I.&Plastow G.S. (1998).Prolactin receptor gene is associated with increased litter size in pigs. Swine Research Report.11: 8-15.

    Ziólkowska Agata, Bogdzínska Maria, Biegniewski Jan (2010). Polymorphism of prolactin receptor gene (PRLR) in the Polish Landrace and Polish Large white swine population and reproductive traits. Journal of Central European Agriculture.11(4):443-448.