Laboratory Evaluation of Efficacy of Inactivated Vaccine Using TheCanine Distemper CDV-VNUA-768 Strain

Received: 03-11-2015

Accepted: 14-01-2016

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Issue: Vol. 14 No. 1 (2016)

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NÔNG HỌC

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Nen, T., Lan, N., Hoa, N., & Nam, N. (2024). Laboratory Evaluation of Efficacy of Inactivated Vaccine Using TheCanine Distemper CDV-VNUA-768 Strain. Vietnam Journal of Agricultural Sciences, 14(1), 21–27. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/254

Laboratory Evaluation of Efficacy of Inactivated Vaccine Using TheCanine Distemper CDV-VNUA-768 Strain

Tran Van Nen (*) 1 , Nguyen Thi Lan 1 , Nguyen Thi Hoa 1 , Nguyen Huu Nam 1

  • 1 Khoa Thú y, Học viện Nông nghiệp Việt Nam

    • Keywords

    CDV, inactivated vaccine, protected capacity

    Abstract


    Canine distemper inactivated vaccines produced from CDV-VNUA-768 strain virus were evaluated for theirprotected capacity dogs by inoculating with CDV-HUA-04H strain virus. Six female Beagle dogs (six weeks old) were injected with the vaccine produced from CDV-VNUA-768 strain virus and inoculating with CDV-HUA-04H strain virus after 3 week post injection. Antibody response in dogs after vaccination against Canine distemper virus was examined by ELISA. Antibody contentsreached above critical level after 21days of vaccination andmaximum value during 35-42thday (titer mean of antibody was 1.54) after vaccination. Between from 42thday to 49thday after vaccination, antibody contents decreasedbut maintained above the critical level at49thday (titer meanof1.35). After 21 day post inoculation with CDV-HUA-04H strain virus, the vaccine groups produced specific antibody for canine distemper virus with titer mean above critical level (0.69). Result of this study showed that dogs were protected with 100 percent when they were injected with inactivated vaccine produced from CDV-VNUA-768.

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