Experimental Study on Combining Nanosilver and Florfenicol in the Treatment of Aeromonas veroniiDisease on Channel Catfish (Ictalurus punctatus)

Received: 17-12-2020

Accepted: 01-03-2022

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CHĂN NUÔI – THÚ Y – THỦY SẢN

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Dung, N., Dung, L., Van, K., & Hoai, T. (2024). Experimental Study on Combining Nanosilver and Florfenicol in the Treatment of Aeromonas veroniiDisease on Channel Catfish (Ictalurus punctatus). Vietnam Journal of Agricultural Sciences, 20(4), 475–483. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/978

Experimental Study on Combining Nanosilver and Florfenicol in the Treatment of Aeromonas veroniiDisease on Channel Catfish (Ictalurus punctatus)

Nguyen Thi Dung (*) 1 , Le Viet Dung 1 , Kim Van Van 1 , Truong Dinh Hoai 2, 3, 4

  • 1 Khoa Thủy sản, Học viện Nôngnghiệp Việt Nam
  • 2 Khoa Chăn nuôi và NTTS
  • 3 Faculty of Animal Science and Aquaculture, Vietnam National University of Agriculture
  • 4 Khoa Thủy sản, Học viện Nông nghiệp Việt Nam
  • Keywords

    Nano-silver, florfenicol, A. veronii, Channel catfish

    Abstract


    This study aimed to evaluate the antibacterial potential of florfenicol and nanosilver combination for the treatment of bacterial infection caused by Aeromonas veronii in channel catfish. The susceptibility of A. veroniito nanosilver and the antibiotic florfenicol was evaluated in vitrovia measurement of inhibited zone based on the diffusion methods. The in vivoexperimental treatment was performed by challenging healthy Channel catfish at LD50 and by feeding with the supplement with different formulations of florfenicol and nanosilver. The results of in vitroexperiments showed that the combination of 10ppm florfenicol and 5ppm nanosilver resulted in the inhibited zone comparable to that of conventional use of antibioticflorfenicol (15ppm). After 7 days of treatment, the combination of florfenicol and nanosilver antibiotics had a similar therapeutic effect compared to those using antibiotics alone.

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