Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC.

Received: 26-11-2015

Accepted: 29-05-2016

DOI:

Views

0

Downloads

0

Issue: Vol. 14 No. 5 (2016)

Section:

KỸ THUẬT VÀ CÔNG NGHỆ

How to Cite:

Kha, T., Hoan, H., & Hien, N. (2024). Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC. Vietnam Journal of Agricultural Sciences, 14(5), 779–784. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/293

Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC.

Trinh Dinh Kha (*) 1 , Ha Thi Thanh Hoan 1 , Nguyen Thi Thu Hien 2

  • 1 Trường Đại học Khoa học, Đại học Thái Nguyên
  • 2 Trường Đại học Nông lâm, Đại học Thái Nguyên

    • Keywords

    Chemical composition, extract, Mahonia nepalensis DC., Staphylococcus aureus, inhibitory activity

    Abstract


    An investigation was conducted to determine the chemical composition and inhibitory effect against Staphylococcus aureus of Mahonia nepalensis DC. (M. nepalensis) extract. Chemical analysis showed that the extract contained alkaloids, tannins, flavonoids, saponins and terpenoids. The growth of Staphylococcus aureus strain was inhibited by the different extract concentrations. The diameter of inhibition zones varied from 10 to 15 mm for the extract concentrations from 20-40 mg/ml. The MIC, IC50 and MBC values were 0.05; 4.17 and 21.67 mg/ml, respectively. It is, therefore, suggested that the extract from M. nepalensis could be used as an anti-Staphylococcus agent in particular and a promising antibacterial agent in general.

    References

    Al-Younis N. K. and Abdullah A. F. (2009). Isolation and antibacterial evaluation of plant extracts from some medicinal plants in Kurdistan region. J Duhok Univ., 12: 250-255.

    Coutinho H. D. M., Costa J. G. M., Siqueira-Júnior J. P., Lima E. O. (2008). In vitro anti-staphylococcal activity of Hyptis martiusii Benth against methicillin-resistant Staphylococcus aureus-MRSA strains. Brazilian Journal of Pharmacognosy,18: 670-675.

    Cowan M. M. (1999). Plants products as antimicrobial agents. Clin Microbiol Rev., 12: 564- 582.

    Dinges M. M., Orwin P. M. and Schlivert P. M. (2000). Exotoxins of Staphylococcus aureus. Clin Microbiol Rev., 13: 16-34.

    Nguyễn Thượng Dong (2006). Nghiên cứu thuốc từ thảo dược. Nhà xuất bản Khoa học và Kỹ thuật, Hà Nội.

    Elakkia S. A. and Venkatesalu V. (2014). Anti-MRSA activity of different extracts of selected Cassia species. International Journal of Pharmaceutical and Clinical Science, 4: 11-17.

    Harborne J. B. (1978). Phytochemical methods (3rded.). Chapman and Hall, London.

    Hwang F. L., Jan S. L., Chen P. Y., Chi C. S., Wang T. M., Fu Y. C., Tsai C. R. and Chang Y. (2002). Left ventricular dysfunction in children with fulminant Enterovirus 71 infecton: An avaluation of the clnical course. Clin Infect Dis., 34: 1020-1024.

    Đỗ Tất Lợi (2008). Những cây thuốc và vị thuốc Việt Nam. Nhà xuất bản Y học, Hà Nội.

    Lyon B. and Skurrayr R. (1987). Antimicrobial resistance of Staphylococcus aureus. Genetic basis Microbiol Rev., 51: 88-134.

    NCCLS-National Committee for Clinical Laboratory Standards (2002). Performance standards for antimicrobial disk susceptibility tests. documentM100-S12, Pennsylvania.

    Rubens D. M., Constantin O. O., Moevi A. A., Nathalie G. K., Daouda T., David N. J., Mireille D. and Joseph D. A. (2015). Anti Staphylococcus aureus activity of the aqueous extract and hexanic fraction of Thonningia sanguinea (Cote ivoire). International Journal of Pharmacognosy and Phytochemical Research, 7: 301-306.

    Wang J. T., Chang S. T. and KoW. J. (2001). A hospital acquired outbreak of Methicillin - resistant Staphylococcus aureus infection initiated by a surgeon carrier. J Hos Infec., 47: 104-109.