Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC.

Received: 26-11-2015

Accepted: 29-05-2016

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Issue: Vol. 14 No. 5 (2016)

Section:

KỸ THUẬT VÀ CÔNG NGHỆ

How to Cite:

Kha, T., Hoan, H., & Hien, N. (2024). Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC. Vietnam Journal of Agricultural Sciences, 14(5), 779–784. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/293

Chemical Compositionand Staphylococcus aureusInhibitory Activity of the Ethanol Extract from Mahonia nepalensisDC.

Trinh Dinh Kha (*) 1 , Ha Thi Thanh Hoan 1 , Nguyen Thi Thu Hien 2

  • 1 Trường Đại học Khoa học, Đại học Thái Nguyên
  • 2 Trường Đại học Nông lâm, Đại học Thái Nguyên

    • Keywords

    Chemical composition, extract, Mahonia nepalensis DC., Staphylococcus aureus, inhibitory activity

    Abstract


    An investigation was conducted to determine the chemical composition and inhibitory effect against Staphylococcus aureus of Mahonia nepalensis DC. (M. nepalensis) extract. Chemical analysis showed that the extract contained alkaloids, tannins, flavonoids, saponins and terpenoids. The growth of Staphylococcus aureus strain was inhibited by the different extract concentrations. The diameter of inhibition zones varied from 10 to 15 mm for the extract concentrations from 20-40 mg/ml. The MIC, IC50 and MBC values were 0.05; 4.17 and 21.67 mg/ml, respectively. It is, therefore, suggested that the extract from M. nepalensis could be used as an anti-Staphylococcus agent in particular and a promising antibacterial agent in general.

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