Received: 30-05-2016 / Accepted: 16-10-2016
Maceration extraction of Caesalpinia sappan L. (CS) in ethanol solvent (96%) followedby steam distillation at 80-90oC resulted in an average extract efficacy of 6.80%. Ten percent extract sollution showed inhibitory effects on E. coli. The effectswere concentration-dependent and higher on standard E. colistrain in comparison to those on chicken-derived isolates. The strain dependent inhibition was similarly observed for doxycycline, ciprofloxacin and colistin. The 10% sollution of CS extract exerted preventiveand treatment effects on experimental infection with E. coliin Yellow-featherchickens. The results can be considered asscientific basisfor further studies on prevention and treatment potentialof CS extracts.