Received: 28-03-2023
Accepted: 04-08-2023
DOI:
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Evaluation of Effects of Herbal Product PremixHad and Doxycycline on Feed Conversion Ratio and Small Intestinal Villus Measurements in Swiss albino Mice
,
Vu Van Cuong
2
,
Nguyen Thi Minh Phuong
2
,
Do Van Hieu
3
,
Phuong Thien Thuong
4
,
Nguyen Duc Hung
4
,
Nguyen Ba Tiep
2, 5
Keywords
Doxycycline, PremixHad, safety, small intestinal villi, Swiss albino mice
Abstract
Thí study aims to evaluate the effectiveness of herbal product PremixHad and doxycycline on feed intakes, feed conversion ratios and villus measurements of small intestine in Swiss albino mice via growth parameters and micro-morphological measurements. The results showed that PremixHad supplement in feed with concentrations of 1.25%; 2.5%; 5.0% and doxycycline (2g per liter of drinking water) were safe for the mice. Supplement concentation at 1.25% improved BW gain. PH and doxycycline increased feed efficiency via the decrease of FCR. PH showed good effects on height, width and height/width ratios of duodenal and jejunal villi but no effect on ileal villus sizes. Meanwhile, doxycycline decreased these parameters in the mouse illeum. It can be said that PH is safe with positive effects on the intestinal health of Swiss albino mice and should be tested in livestock animals to confirm the effectiveness.
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