Ngày nhận bài: 20-06-2014
Ngày duyệt đăng: 02-03-2015
DOI:
Lượt xem
Download
Cách trích dẫn:
INFLUENCE OF INTESTINAL GOBLET CELL BY EimeriavermiformisINFECTION ON THE EXPULSION OF NippostrongylusbrasiliensisIN CO-INFECTED HOST
Từ khóa
Goblet cell, Nippostrongylus brasiliensis, Eimeria vermiformis
Tóm tắt
Goblet cell plays an important role on expulsion of Nippostrongylus brasiliensis by increase in the number in intestine. In contrast, infection with Eimeria vermiformis lead to decrease goblet cell number. On the other hand, Eimeria vemiformis results in the development of small intestinal Th1-type and infection of Nippostrongylus brasiliensis results on development of Th2-type response. This paper discussed the influence of goblet cell in co-infected host on elimination of Nippostrongylus brasiliensis. For this purpose, Nippostrongylus brasiliensis and Eimeria vermiformis were infected to ICR mice, expulsion of the worm were delayed in co-infected group compare to single infected group and associated with the changes of goblet cell number. The results clearly showed that Eimeria vermiformis infection influenced to the delay of elimination of Nippostrongylus brasiliensis in immune group. Thus, the influence may effect through immune system was suggested.
Tài liệu tham khảo
Deplancke, B and Gaskins, H.R. (2001). Microbial modulation of innate defence: goblet cells and the intestinal mucus layer. Am J ClinNutr.,73: 1131S-1141S.
Ishikawa N, Horii Y, OinumaT, SuganumaT, NawaY. (1994). Goblet cellmucinsas the selective barrier for the intestinal helminths: T-cell-independentalterationof goblet cell mucins by immunologically ‘damaged’ Nippostrongylusbrasiliensisworm and its significance on the challenge with homologous and heterelogousparasite. Immunology, 81: 480-486.
Kopf, M., Le Gros, G., Bachmann, M., Lamers, M.C., Bluethmann, H., and Kohler, G. (1993). Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature, 362: 245-248.
Longphre, M., Li, D., Gallup, M. (1999). Allergen induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells. J ClinInvest., 104: 1375-1382.
Marshall, A.J., Brunet, L.R., van Gessel, Y., Alcaraz, A., Bliss, S.K., Pearce, E.J., and Denkers, E.Y. (1999). Toxoplasma gondiiand Schistosoma mansonisynergize to promote hepatocyte dysfunction associated with high levels of plasma TNF-alpha and early death in C57BL/6 mice. J. Immunol., 163: 2089-2097.
McKenzie, G.J., Fallon, P.G., Emson, C.L., Grencis, R.K., and McKenzie, A.N. (1999). Simuntaneousdisruption of interleukineIL-4 and IL-13 defines individual roles in T helper cell type 2-mediate response. J. Exp. Med., 189: 1565-1572.
Mesfin, G.M and Bellamy, J.E.C. (1979).Effect of acquired resistance on infection with E. falciformisvar. pragensisin mice. Infect. Immun., 23: 108-114.
Miller, H.R.P. and Nawa, Y. (1979). Nipostrongylusbrasiliensis: intestinal goblet cell response in adoptively immunized rats. Exp. Parasitol., 47: 81.
Miller, H.R.P., Woodbury, R.G., Huntley, J.F., Newlands, G. (1983). Systemic release of mucosal mast cell protease in primed rats challenged with Nippostrongylusbrasiliensis. Immun., 49: 471-479.
Nawa, Y., Ishikawa, N., Tsuchiya, K., Horii, Y., Abe, T., Khan, A.I., Shi, B., Itoh, H., Ide, H., and Uchiyama, F. (1994). Selective effector mechanism for expulsion of intestinal helminths. Parasite Immunol., 16: 333-338.
Ogilvie, B.M., and Hockley, D.J. (1968). Effect of immunity of Nippostrongylusbrasiliensisaldultworms: reversible and irreversible change in effectivity, reproduction and morphology. J. Parasitol., 54: 1073-1084.
Oliver, L., Ildiko, R.D., and Klaus, J.E. (2004). Infection with Toxoplasma gondiireduce established and developing Th2 responses induced by Nippostrongylusbrasiliensisinfection. Infection and immunity, 72(7): 3812-3822.
Rose, M. E., D. G. Owen, and P. Hesketh(1984). Susceptibility to coccidiosis: Effect of strain of mouse on reproduction of EimeriavermiformisParasitology, 88: 45-54.
Rose, M.E., Millard, B.J and Hesketh, P. (1992). Intestinal changes associated with expression of immunity to challangewith Eimeriavermiformis. Infect. Immun., 60(12): 5283-5290.
Smith, A.L and Hayday, A.C. (2000).Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeriavermiformis. Infect. Immun., 68(11): 6273-6280.
Temann, U.A., Prasad, B., Gallup, M., W. (1997). A novel role for murine IL-4 in vitro: induction of MUC5AC gene expression and mucin hypersecretion. Am J RespirCell MolBiol., 16: 471-478.
Tomita, M., Itoh, H., Ishikawa, N., Higa, A., Ide, H., Marukumo, Y., Maruyama, H., Koga, Y and Nawa, Y. (1995). Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes. Biochem., 311: 293-297.
Wells, P.D. (1963). Mucin secrectingcells in rats infected with Nipostrongylusbrasiliensis. Experimental Parasitology, 14(1): 15-22.
William, G.C.H., Antony, J.C., Claire, J.H., Helen, M., Elmarie, M., Berenice, A., Fred, D.F., Gary, K.O., Dave, E., Frank, B. (2007). Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expusionin SMC-specific IL-4Rα- deficient mice. PlosPathog., 3(1): 0046-0053.
Urban, J.F., Noben-Trauth, N., Donaldson, D.D., Madden, K.B., Morris, S.C., Collins, M., and Finkelman, F.D. (1998). IL-13, IL-4α, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Niposstrongylusbrasiliensis. Immunity, 8: 255-264.
Yunus, M., Horii, Y., Makimura, S and Smith, A. (2005). Murine goblet cell hyperplasia during Eimeriapragensisinfection is ameliorated by clindamycin treatment. J. Vet. Med. Sci., 67(3): 311-315.