MICROWAVE-ASSITED SYNTHESIS OF COUMARIN DERIVATIVES

Ngày nhận bài: 17-02-2016

Ngày duyệt đăng: 08-05-2016

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Số: Tập 14 Số 6 (2016)

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KỸ THUẬT VÀ CÔNG NGHỆ

Cách trích dẫn:

Mai, N., & Hanh, N. (2024). MICROWAVE-ASSITED SYNTHESIS OF COUMARIN DERIVATIVES. Tạp Chí Khoa học Nông nghiệp Việt Nam, 14(6), 907–912. http://testtapchi.vnua.edu.vn/index.php/vjasvn/article/view/309

MICROWAVE-ASSITED SYNTHESIS OF COUMARIN DERIVATIVES

Nguyen Thi Thanh Mai (*) 1 , Nguyen Thi Hong Hanh 2

  • 1 Faculty of Chemistry, Hanoi University of Industry
  • 2 Faculty of Environment, Vietnam National University of Agriculture

    • Từ khóa

    Coumarin, synthesis, antibacterial and antifungal activity

    Tóm tắt


    Some coumarin derivatives possess high biological activities, such as antispasmodic effects, dilating the coronary arteries, anticoagulants, psoriasis treatment, and antibacterial, antifungal and anti-inflammatory activity. Some derivatives also exert inhibitory effect on HIV. In this study, we performed a microwave-assisted solvent-free synthesis of coumarins from using conjugate nucleophilic reactions with various amines and achieved 55-70% efficiency. The products synthesized exhibit antibacterial and antifungal activity.

    Tài liệu tham khảo

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